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Fonds has been arranged into seven (7) series: (1) Hospital Board and Committee Minutes and Financial Records, Auxiliary Records and Minutes; (2) Studies, Publications and Discussion Papers; (3) Books and Publications; (4) Building of the Port Hope & District Hospital; (5) Certificates and Plaques; (6) Photographs and Videos; (7) History, Minutes, and Miscellaneous.

Photographs from World War Two, Philip Etters identification cards, literature on the navy and military, correspondances with the Canadian Merchant Navy Veterans Association, newspaper articles, newspapers from World War Two, House of Commons releases, the journal "The Red Duster".

Fonds consists of four (4) blueprints/floor plans of the Port Hope Hospital that was located on Ward Street, c1915. The blueprints were created for the construction of the "old" hospital by Ellis & Ellis Architects, Toronto. They include: First Floor, Second Floor, East Elevation, and South Elevation.

This series contains records concerning the involvement of the Sisters of St. Joseph of Pembroke with St. Joseph’s Hospital in Barrhead, Alberta. The records cover the establishment of the hospital, the administration and operation of the hospital, the transfer of the hospital, and the Sisters’ involvement with the Catholic Hospital Association and the Alberta Hospital Association. Materials include financial records, agreements for the purchase and sale of property, annals, memoirs, pamphlets, booklets, newsletters, lot maps, hospital floor plans, hospital bylaws, correspondence, and photographs. The major topics within the correspondence include establishing and operating the hospital, finances, the purchase and sale of property, construction and renovations, Catholic hospitals and medical ethics in Alberta, the changing role of Sisters in the hospital, and the relinquishing of ownership of the hospital. The photographs are of the hospital and Sisters at various events and locations.

The fonds consists of records relating to Edwin Seaborn's medical and military careers, research, and personal records. Included are ledgers, research notes, correspondence, programmes, invitations, scrapbooks, postcard collection, photographs, books, newspaper clippings; and copies of diaries, letters and reminiscences of various Middlesex County residents dating. The fonds consists of records created between 1883 - 1951.

This fonds consists of letters, manuscripts, articles, poems, addresses, lectures, journals, reports, notes, reviews, invitations, photographs, posters, negatives, drawings, maps, receipts, crafts, electroplates, and other materials relating to Dr. Richard Maurice Bucke and his family. In addition there is substantial material related to his work as Superintendent of the London Asylum for the Insane and to his friends (especially Walt Whitman) and other studies.

This fonds consists of Vesey Brown’s medical education and military certificates and personal correspondence, as well as material relating to Brown and Masingberd family property in London and Morpeth, Ontario. Majority of fonds consists of Series 4 that is Brown's work as watercolour artist, mainly depicting London, Port Stanley and Elgin County.

This fonds contains lecture papers, certificates and member records.

Fonds consists of financial and organizational records of the Abbeyfield Housing Society of Shanty Bay, who were responsible for the construction and early operation of O'Brien House, a retirement home.

The collection contains photos dating from 1960 and 1961. The photos show nurses, assistant nurses and nuns working at Notre-Dame Hospital in Hearst.

The collection contains digital photos dating from 1898 to 1954. Most of them show members of the Coulombe family when they were living in Hearst, including Eveline's parents as well as her siblings: André, Cécile, Georgette, Léo, Robert and Yvonne. In addition, there are some pictures of their neighbors and friends from Hearst, such as Claude Larose's family. Others illustrate students at école Sainte-Thérèse and a few buildings in Hearst, at that time. There are also textual documents that the donor has kept, as souvenirs from her childhood in Hearst. It includes an autograph album where we find the signature of several people living in Hearst in the early 1940s, as well as religious images and correspondence.

Sous-fonds contains correspondence, newsletters, documentaries, project files, school donor files, publications, and records of the administration of and work supported by Heart-Links.

This series consists of material created by and collected about Mother Constance Dunn. This includes biographical research; a bound New Testament owned by Mother Constance Dunn; photographs of Mother Constance Dunn and her sister, Sister Norberta Dunn; correspondence concerning a new Motherhouse, the foundation of the hospital in Sarnia; jubilees; correspondence, some written in Latin, with the Bishop of London, John T. Kidd, and the Archbishop of Edmonton, J. H. MacDonald, concerning the canonical status of the Edmonton community (the canonical status, governance, and fiscal responsibility of the Edmonton community had been an ongoing issue since the Edmonton community had been founded by the Sisters of St. Joseph of London in 1922); and letters from Bishop Dignan of Sault Ste. Marie to Mother Constance expressing his condolences on the deaths of several Sisters.

The first subseries consists of biographical chronologies and speaking notes including a presentation to the St. Joseph’s Hospital Board in 1987. Included are copies of her educational achievement certificates and information about her membership in Sigma Theta Tau, the National Honor Society of Nursing, United States. There are several photographs and newsclippings from various times throughout her ministry. Highlights from the correspondence include exchanges with Bishop Sherlock, Bishop of London, an appeal to the federal government for aid to Ethiopia and a reply from the Minister of External Affairs, and a letter from the Vice-Chancellor granting approval to establish at chapel at a mission house in 1979. Copies of speaking notes for a variety of presentations are included with event programs. There are several letters of congratulations and greeting cards. There are a few mementos of her trip to Rome.

The series consists of records kept by the General Superior office for use in the administration of the community in London, Ontario. Material is primarily from the period during which Sister Margo Ritchie held the office, but it also contains material from when Sister Mary Diesboug and Sister Valerie Van Cauwenburghe held the position. This series contains twelve subseries relating to the operations, missions, and activities of the congregation. This includes the Medaille Retreat House, Josephs’ House, the Detox Centre, My Sister’s Place, St. Joseph’s Hospitality Centre, Elizabeth Place, St. Stephen’s House, the Southdown Project, Holy Rosary House in Windsor, the Goderich convent, and the Sisters of St. Joseph in Alberta. There is also material related to the hospitals in London, Sarnia, and Chatham administered by the Sisters and the transfer of operation of said hospitals to the Chatham-Kent Health Alliance and St. Joseph’s Health Care Society. There is material related to the construction of a new residence, especially concerning the Leadership in Energy and Environmental Design (LEED) standards of the new building, and relocation of the Sisters from Mount St. Joseph to this new residence.

There is also material related to the various meetings of the congregation, from the more informal Community Days to the more formal Assemblies and Chapters. Chapters are formal congregational meetings where major decisions, such as amalgamation and leadership positions were voted on. There are voting records from the 2011 Special Chapter and the 2009 Oneness Project in this series. There are also reports from the Leadership Circle, Chapters, and committees within the congregation. There is also material from the Federation of the Sisters of St. Joseph of Canada, an organization made up of all the Congregations of the Sisters of St. Joseph in Canada. There is material from the Federation and the London congregation’s systemic justice efforts and the Sisters’ efforts towards concerning the Truth and Reconciliation Commission. There are various newsletters from the Federation and the London congregation. The series also includes administrative correspondence and speeches presented by the General Superior to the congregation.

In summary, the series contains letters, reports, speeches, minutes, voting records, newsletters, pamphlets, prayer books, agendas, meeting minutes, memorandums, postcards, photographs, correspondence, timelines and schedules, inventory lists, legal documents, meeting minutes, executive summaries, budget reports, reports, newspaper and magazine clippings, bursary reports, histories, bulletins, designs for stained glass windows, and property appraisals.

This series contains records related to general roles and duties that Sisters held in their ministries. There are also records concerning specific professional roles, including homemaker, nurse, music teacher and teacher. Records take the form of handwritten and typed notes on the ministries performed by individual sisters in 1999, and lists of sisters that performed specific roles in the congregation.