The Sisters of St. Joseph built St. Mary’s Hospital at 200 Grosvenor Street in 1951. It received its first 35 patients on April 3, 1951 from the House of Providence. It was created to serve the special medical and nursing needs of the chronically ill. The Sisters assigned to St. Mary’s Hospital in 1951 were: Sr. Patrick Joseph as Superior; Sr. Leonora Doyle as Superintendent of the Hospital; Sisters: Irene Redmond, Austin Gurvine, Christina Dewan, Alberta Kenny, Lutgarde Stock, Bernandine Boyle, St. Matthew McMurray, Gervase Martin, Roseanne Sheehan, Ludmille (Isabel) Girard, Carmela Reedy, Justina Mahoney, Vincent de Paul Cronin, Genevieve Anne Cloutier, Dolores Sullivan. Its physiotherapy department was especially well-known for its efficiency, modern equipment, and well trained staff.
Many patients at St. Mary’s were there for long-term care and were encouraged to make the hospital their home. Some of the programs that facilitated this were the Patients’ Council, a patient newspaper called Between Friends, and fund-raising events for charities and the hospital. The hospital’s budget was often strained. In 1959, the Ontario Hospital Commission Insurance was created which provided welcome financial relief for many hospitals, including St. Mary’s. It was difficult for administrative and medical staff to adjust with extra patient evaluations and paperwork required to qualify for insurance.
In 1960, the hospital re-organized its staff in preparation for the Canadian Council Accreditation Survey which the hospital passed. The hospital maintained its accreditation over the years despite inadequate facilities which were addressed in 1979-1981 with a large building project. The old laundry and what remained of the Mount Hope Chapel were demolished to make way for a new chapel, laundry, and kitchen which connected the hospital with the neighbouring Marian Villa. In 1979, the Pastoral Department was created at the hospital. A Sister or priest worked part-time to co-ordinate the Sisters who volunteered for pastoral visits to patients.
In 1985, St. Mary’s Hospital merged with St.Joseph’s Hospital and Marian Villa to become St. Joseph’s Health Centre. In 1986, rehabilitation services were added at St. Mary’s Hospital for acute injuries, amputees, neurological, orthopaedic, and chronic pain. In 1997, it became part of the Mount Hope Centre for Long Term Care.